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Ahoefa Vovor1, Ameyo Dorkenoo1, Yao Layibo2
1Faculté Mixte de Médecine et de Pharmacie, Université de Lomé, Togo.
Insights
The HemoCue Hb201+ device shows good sensitivity for diagnosing anemia in children in Togo, aiding peripheral health centers. While precision is average, it facilitates crucial hemoglobin level determination in accessible areas.
Area of Science:
- Clinical diagnostics
- Hematology
- Public health
Context:
- Anemia is a significant global health issue, particularly in developing nations.
- Accurate hemoglobin level measurement is vital for effective anemia diagnosis and management.
- Peripheral health facilities often lack advanced diagnostic tools.
Purpose:
- To assess the diagnostic accuracy and performance of the HemoCue Hb201+ device.
- To compare HemoCue Hb201+ results with standard hematology analyzers.
- To evaluate the utility of HemoCue Hb201+ in resource-limited settings.
Summary:
- The HemoCue Hb201+ demonstrated high sensitivity (95.1%) and good precision (72.8% within ±1g/dL) in diagnosing anemia in children aged 6-59 months.
- A strong correlation (Pearson coefficient 0.80) was observed between HemoCue and reference analyzer results.
- Anemia prevalence was similar using both methods (79.3% reference vs. 77.9% HemoCue).
Impact:
- The HemoCue Hb201+ can effectively support anemia diagnosis in peripheral health centers in Togo.
- Its use can improve the management of anemia in remote populations with limited access to laboratory services.
- The device offers a practical solution for point-of-care hemoglobin testing in resource-constrained environments.
Abstract:
Performance of HemoCue Hb201+ in the diagnosis of anaemia in children in health facilities at the peripheral level in Togo.
Background:
Anaemia is a global public health problem, especially in developing countries. Anaemia has major repercussions on health status, as well as on the economic and social development of a country. Effective care of anaemic patients requires a reliable and precise diagnostic test that can determine haemoglobin levels.
Objective:
To evaluate the diagnostic performance of the Hemocue test Hb201+®.
Method:
This study compared haemoglobin levels measured using the photometer Hemocue Hb201+® with those measured by analysers of haematology. Children aged 6 to 59 months who suffered from uncomplicated malaria were eligible for inclusion. Haemoglobin levels determined by the analysers were considered the reference for evaluation of the levels measured using Hemocue Hb201+®.
Results:
72.8% of the values obtained by Hemocue Hb201® were within ±1g/dl of the reference value. The Pearson correlation coefficient was 0.80. The prevalence of anaemia was 79.3% using the reference method and 77.9% using Hemocue 201+®. The sensitivity and the specificity of Hemocue Hb201+® were 95.1% and 65.3% respectively.
Conclusion:
The study results showed that the Hemocue Hb201 test+® provided good sensitivity, average specificity and average precision, both for the diagnosis of anaemia and for the determination of haemoglobin levels. It may be used in peripheral centres to facilitate the laboratory diagnosis of anaemia and its management in populations that live in areas with difficult accessibility.