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Use of hydroxyurea in French-speaking Sub-Saharan Africa
Jean-Benoît Arlet1, Françoise Bernaudin2, Indou Deme-Ly3,4
1Department of Internal Medicine, Georges Pompidou European Hospital, AP-HP, French National Reference Center for Sickle Cell Anemia, Thalassemia, Other Rare Red Blood Cell Disorders and Erythropoiesis, Paris, and Université Paris-Cité, Paris, France. jean-benoit.arlet@aphp.fr.
None:
The hydroxyurea is a save, affordable and essential medicine for sickle cell disease (SCD), reducing painful crises and mortality. To foster the prescription of hydroxyurea for patients with SCD in sub-Saharan African countries, the scientific advisory board of Drep.Afrique, a non-governmental organization dedicated to SCD in Africa, has developed a therapeutic guideline well suited to conditions on the ground. These guidelines answer three essential questions: which patients should be prioritized for treatment with hydroxyurea, which dose should be used, and what follow-up should be implemented in those low-resources countries? The guidelines are given as in a concise document for easy use by practitioners on the ground, available in English and in French.
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