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Updated: Aug 5, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
Spontaneous regression of B-cell acute lymphoblastic leukemia with PAX5 alterations at relapse: a case report
Vadim Lesan1, Joerg Bittenbring2, Sarah Altmeyer2
1Department of Hematology and Oncology, Saarland University Hospital, Kirrberger Street 100, 66421, Homburg, Germany. vadimlesan92@gmail.com.
Abstract:
Acute lymphoblastic leukemia is the most common pediatric hematological disease representing less than 1% of hematological diseases in adults. The prognosis of ALL improved significantly in the last decades. Almost all patients require a therapy at the time of diagnosis. Rare cases of spontaneous remission of ALL have been described. We report a case of B-ALL that underwent spontaneous remission after an episode of infection and describe the cytogenetic changes associated with this uncommon clinical presentation of B-ALL.
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