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Related Experiment Video

Updated: Feb 19, 2026

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates
08:32

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates

Published on: October 3, 2017

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Nonhuman Primate Optogenetics: Recent Advances and Future Directions.

Adriana Galvan1, William R Stauffer2, Leah Acker3

  • 1Yerkes National Primate Research Center and Department of Neurology, School of Medicine, Emory University, Atlanta, Georgia 30329, agalvan@emory.edu.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|November 10, 2017
PubMed
Summary

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Optogenetics uses light to control neural activity, offering insights into brain function. Applying this technique to nonhuman primates (NHPs) advances our understanding of human cognition and neurological disorders.

Area of Science:

  • Neuroscience
  • Genetics
  • Primate Research

Background:

  • Optogenetics enables precise control of neural activity using light-gated opsins.
  • Understanding the neural basis of behavior requires advanced tools for specific cell targeting.

Purpose of the Study:

  • To review advances in optogenetics for nonhuman primates (NHPs).
  • To highlight the utility of NHPs as models for human brain function and dysfunction.
  • To summarize the impact of optogenetics on understanding primate brain function.

Main Methods:

  • Review of recent optogenetic studies in NHPs.
  • Analysis of technical challenges and solutions in primate optogenetics.
  • Summarization of experimental findings from optogenetic interventions.
Keywords:
NHPmonkeyopsinsoptogeneticoptrodepromoter

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Related Experiment Videos

Last Updated: Feb 19, 2026

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates
08:32

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates

Published on: October 3, 2017

8.5K
A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates
08:41

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

5.4K
In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

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Main Results:

  • Significant technical hurdles in primate optogenetics have been overcome.
  • Optogenetic tools are increasingly effective in large, wild-type animals like Rhesus macaques.
  • Optogenetic experiments are yielding new insights into primate neural circuits and behavior.

Conclusions:

  • Optogenetics in NHPs is crucial for studying human cognition and neurological diseases.
  • Further advancements in primate optogenetics promise deeper understanding of brain function.
  • NHPs serve as a vital translational model for human neuroscience research.