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Combining Raman and laser induced breakdown spectroscopy by double pulse lasing.

Vasily N Lednev1,2, Sergey M Pershin3, Pavel A Sdvizhenskii4

  • 1National University of Science and Technology MISiS, Leninsky Ave. 4, Moscow, 119991, Russia. vasilylednev@gmail.com.

Analytical and Bioanalytical Chemistry
|November 10, 2017
PubMed
Summary

This study introduces a novel dual-spectrometry instrument combining Raman and laser-induced breakdown spectroscopy (LIBS) for enhanced sample analysis. The system achieves high-quality spectra and demonstrates quantitative feasibility for diverse materials.

Keywords:
Double pulseLIBSLaser induced breakdown spectroscopyQuantitative analysisRaman scattering

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Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Materials Science

Background:

  • Traditional Raman and Laser-Induced Breakdown Spectrometry (LIBS) offer complementary analytical capabilities.
  • Integrating these techniques into a single platform presents challenges in optimizing measurement conditions for both.
  • A novel approach is needed to leverage the strengths of both Raman and LIBS without compromising spectral quality or sample integrity.

Purpose of the Study:

  • To develop and validate a single-instrument system combining Raman spectrometry and LIBS.
  • To demonstrate the feasibility of acquiring high-quality Raman and LIBS spectra simultaneously or sequentially.
  • To showcase the quantitative analysis capabilities of the combined Raman/LIBS instrument.

Main Methods:

  • Utilized a pulsed solid-state Nd:YAG laser in a double-pulse mode for sequential Raman and LIBS measurements.
  • Employed a low-energy pulse for non-destructive Raman analysis followed by a high-energy pulse for LIBS plasma generation.
  • Optimized gating for independent Raman and LIBS spectral acquisition within a single laser event.

Main Results:

  • Acquired high-quality Raman and LIBS spectra from inorganic salts (gypsum, anhydrite) and pharmaceutical samples (acetylsalicylic acid).
  • Demonstrated the first quantitative analysis feasibility using a combined Raman/LIBS instrument by constructing calibration curves for acetylsalicylic acid (Raman) and copper (LIBS) in a gypsum matrix.
  • Confirmed the absence of target thermal alteration during Raman measurements due to optimized laser pulsing.

Conclusions:

  • The developed dual-spectrometry instrument efficiently combines Raman and LIBS capabilities.
  • This integrated approach offers advantages for sample identification, depth profiling, and remote sensing, especially for samples with non-transparent coverings.
  • The demonstrated quantitative analysis feasibility opens new avenues for complex material characterization.