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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Author Spotlight: Exploring the Fermentation Microbiome Through Next-Generation Sequencing
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BeerDeCoded: the open beer metagenome project.

Jonathan Sobel1, Luc Henry1, Nicolas Rotman1

  • 1Hackuarium Association, Renens, Switzerland.

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|November 14, 2017
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Summary
This summary is machine-generated.

Citizen scientists explored the microbial content of 39 bottled beers using next-generation sequencing. The study identified a diverse range of wild yeast species in commercial brews, demonstrating accessible genomic analysis.

Keywords:
beercitizen sciencecrowdfundingmetagenomic

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Area of Science:

  • Genomics
  • Microbiology
  • Citizen Science

Background:

  • Next-generation sequencing (NGS) has transformed life sciences research.
  • Public understanding of genomic and metagenomic technologies and their ethical implications remains limited.
  • Citizen science initiatives can bridge the gap between advanced research and public engagement.

Purpose of the Study:

  • To engage citizens in discussing societal issues surrounding genomic data.
  • To advance scientific understanding of the microbial composition of beer.
  • To demonstrate the feasibility of using accessible methods for metagenomic analysis.

Main Methods:

  • Targeted metagenomic sequencing of the internal transcribed spacer (ITS) region of fungal species.
  • Sample collection and DNA extraction conducted by non-scientists in a community laboratory setting.
  • Analysis of 39 bottled beer samples from five countries.

Main Results:

  • A diverse array of wild yeast species was detected in commercial bottled beers.
  • The project successfully identified the microbial content within the analyzed beer samples.
  • Demonstrated the effectiveness of combining simple lab procedures with advanced sequencing.

Conclusions:

  • Citizen science participation is effective for engaging the public in genomic research.
  • State-of-the-art sequencing technologies can be applied in non-professional laboratory environments.
  • This approach enables the detection and identification of microbial communities in beverages like beer.