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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
936
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

817
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Letter: Peripheral Eosinophilia Does Not Correlate With Endoscopic and Histological Activity in Paediatric Eosinophilic Oesophagitis.

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Related Experiment Video

Updated: Feb 19, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
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Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis

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Overview of paediatric IBD.

David C Wilson1, Richard K Russell2

  • 1Child Life and Health, University of Edinburgh, Edinburgh EH9 1UW, Scotland, UK; Royal Hospital for Sick Children, Edinburgh, Scotland, UK.

Seminars in Pediatric Surgery
|November 12, 2017
PubMed
Summary
This summary is machine-generated.

Inflammatory bowel disease (IBD) is a chronic condition affecting all ages. Understanding its causes and employing multidisciplinary care are key to managing IBD and improving patient lives.

Keywords:
EpidemiologyGuidelinesInflammatory bowel diseaseMicrobiomeTransition

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Area of Science:

  • Gastroenterology and Immunology
  • Pediatric and Adult Chronic Disease Research

Background:

  • Inflammatory bowel disease (IBD) is a chronic, complex immune-mediated disorder with rising global incidence.
  • IBD affects both children and adults, necessitating comprehensive management strategies.

Purpose of the Study:

  • To summarize the current understanding of IBD etiology and management.
  • To highlight the importance of a multidisciplinary approach in treating pediatric and adult IBD patients.

Main Methods:

  • Review of current literature on IBD pathogenesis and treatment.
  • Synthesis of information regarding the interplay of genetics, microbiome, environment, and immune response in IBD.

Main Results:

  • IBD development involves genetic susceptibility, environmental factors, and interactions with the gut microbiome and immune system.
  • Effective IBD management requires a multidisciplinary approach focused on symptom control, growth, and quality of life.

Conclusions:

  • Achieving intestinal mucosal healing is crucial for long-term remission and complication avoidance in IBD.
  • A holistic, multidisciplinary strategy is essential for managing the burden of IBD in children and adults.