Utility of 111In-Cl3 Scintigraphy for Differentiating Between Bone Marrow Reconversion and Bone Metastasis with
Shoji Okuda1, Hironori Nishibori2, Hiroaki Hoshi2
1Department of Radiology, Kizawa Memorial Hospital, Gifu, Japan; and shojiokudaksm@gmail.com.
Indium chloride (111In-Cl3) scintigraphy has been used to evaluate various hematologic diseases for many years. However, there have been few reports on patients with bone marrow reconversion showing high uptake in 111In-Cl3 scintigraphy. Here, we report the case of a 68-y-old man with esophageal cancer who underwent 18F-FDG PET/CT for staging of the disease. In the first lumbar vertebral body, 18F-FDG PET/CT demonstrated high uptake that made it difficult to distinguish bone metastasis from bone marrow reconversion. 111In-Cl3 scintigraphy demonstrated specific findings with high uptake in the lesion, indicating bone marrow hyperplasia or reconversion.
Indium chloride (111In-Cl3) scintigraphy has been used to evaluate various hematologic diseases for many years. However, there have been few reports on patients with bone marrow reconversion showing high uptake in 111In-Cl3 scintigraphy. Here, we report the case of a 68-y-old man with esophageal cancer who underwent 18F-FDG PET/CT for staging of the disease. In the first lumbar vertebral body, 18F-FDG PET/CT demonstrated high uptake that made it difficult to distinguish bone metastasis from bone marrow reconversion. 111In-Cl3 scintigraphy demonstrated specific findings with high uptake in the lesion, indicating bone marrow hyperplasia or reconversion.
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