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Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence
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[Telomeres and diet quality].

Amelia Marti1, Raquel Echeverría, Lydia Morell-Azanza

  • 1Universidad de Navarra. amarti@unav.es.

Nutricion Hospitalaria
|November 14, 2017
PubMed
Summary

Diet quality impacts telomere length, a marker of health. Adhering to a Mediterranean diet, rich in fruits and vegetables, is linked to longer telomeres, potentially protecting cellular aging.

Area of Science:

  • Nutritional Science
  • Genetics
  • Aging Research

Background:

  • Telomere length is a biomarker for aging and overall health.
  • Limited research exists on diet quality's impact on human telomere integrity.
  • Understanding this relationship can inform precision nutrition strategies.

Purpose of the Study:

  • To systematically review existing evidence on the relationship between diet quality and telomere length.
  • To explore the influence of specific nutrients, foods, and dietary patterns on telomere homeostasis.

Main Methods:

  • Bibliographic review of PubMed database (English/Spanish) up to December 2016.
  • Inclusion of human studies: cross-sectional, case-control, cohort, and intervention.
  • Keywords: diet, nutrients, food, dietary patterns AND telomere length, telomere attrition.

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Main Results:

  • Positive association found between longer telomeres and Mediterranean diet adherence, fruit, and vegetable intake.
  • Inconsistent results for other dietary factors.
  • Processed meats, cereals, alcohol, and sweetened beverages potentially linked to shorter telomeres.

Conclusions:

  • Dietary interventions, especially promoting a Mediterranean-style diet, may protect telomere integrity.
  • Further research into specific dietary components and telomere length is warranted.