Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.4K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.4K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

9.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
9.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COG5-congenital disorder of glycosylation diagnosed by whole genome sequencing in siblings with unexplained optic atrophy, macular atrophy, and developmental delay: case report.

Frontiers in neurology·2026
Same author

mGluR6 coordinates cone terminal targeting and synaptic layer assembly during human retinal development.

bioRxiv : the preprint server for biology·2026
Same author

Expert Consensus on Characteristics, Etiology, and Management of Chorioretinal Atrophy in Patients Treated with Voretigene Neparvovec.

Ophthalmology science·2026
Same author

Self-Constructed Macular Buckle for Myopic Macular Hole-Associated Retinal Detachment.

American journal of ophthalmology·2026
Same author

Pentosan Polysulfate Maculopathy Following Subcutaneous Injections for Arthritis.

JAMA ophthalmology·2025
Same author

Pharmacologic Inhibition of YAP/TEAD and Development of New Chorioretinal Atrophy.

JAMA ophthalmology·2025
Same journal

Persistent placoid maculopathy: long term outcomes and prognostic factors.

Retina (Philadelphia, Pa.)·2026
Same journal

ANTI-VEGF THERAPY SWITCHING RETINAL DISEASES: Characterizing Clinical Manifestations and Common Involved Genes: ERRATUM.

Retina (Philadelphia, Pa.)·2026
Same journal

THE EFFICACY AND SAFETY OF SUBRETINAL BALANCED SALT SOLUTION INJECTION IN DIABETIC MACULAR EDEMA WITH HARD EXUDATES: ERRATUM.

Retina (Philadelphia, Pa.)·2026
Same journal

EVALUATING CLINICAL OUTCOMES OF AMNIOTIC MEMBRANE COVERAGE COMBINED WITH EARLY VITRECTOMY IN THE MANAGEMENT OF PERFORATING GLOBE INJURIES.

Retina (Philadelphia, Pa.)·2026
Same journal

Mid-Phase Hyperfluorescent Plaques as a biomarker of disease activity in Central Serous Chorioretinopathy: Clinical Course and Treatment Response - MICRoN report number Ten.

Retina (Philadelphia, Pa.)·2026
Same journal

Severe retinal non-perfusion is associated with fewer retinal lesions on ultra-wide field fundus photography in proliferative diabetic retinopathy.

Retina (Philadelphia, Pa.)·2026
See all related articles

Related Experiment Video

Updated: Feb 18, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.9K

PERIPAPILLARY PACHYCHOROID SYNDROME.

Nopasak Phasukkijwatana1,2, K Bailey Freund3,4, Rosa Dolz-Marco3,4

  • 1Retinal Disorders and Ophthalmic Genetics Division, Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California.

Retina (Philadelphia, Pa.)
|November 15, 2017
PubMed
Summary
This summary is machine-generated.

Peripapillary pachychoroid syndrome (PPS) is a distinct variant of pachychoroid disease spectrum (PDS). PPS features nasal macular fluid and peripapillary choroidal thickening, differentiating it from other PDS conditions.

More Related Videos

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography
10:24

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

14.1K
Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo
08:00

Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo

Published on: July 13, 2015

12.7K

Related Experiment Videos

Last Updated: Feb 18, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.9K
Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography
10:24

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

14.1K
Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo
08:00

Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo

Published on: July 13, 2015

12.7K

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Choroidal Diseases

Background:

  • Pachychoroid disease spectrum (PDS) encompasses various conditions characterized by choroidal thickening.
  • Peripapillary pachychoroid syndrome (PPS) is a newly identified entity within the PDS.

Purpose of the Study:

  • To delineate the distinct clinical and imaging features of peripapillary pachychoroid syndrome (PPS).
  • To characterize PPS as a novel entity within the pachychoroid disease spectrum (PDS).

Main Methods:

  • Retrospective review of 31 eyes diagnosed with PPS.
  • Comparison of choroidal thickness with age-matched controls: typical PDS and normal eyes.
  • Utilized fundus autofluorescence, fluorescein angiography, and indocyanine green angiography.

Main Results:

  • PPS eyes showed thicker nasal versus temporal macular choroids (P < 0.0001), unlike typical PDS.
  • Intraretinal/subretinal fluid often overlaid dilated peripapillary vessels (pachyvessels).
  • Common findings included choroidal folds, hyperopia, short axial lengths, and other PDS features.

Conclusions:

  • Peripapillary pachychoroid syndrome is a distinct PDS variant with unique peripapillary choroidal thickening and nasal macular fluid.
  • Distinguishing PPS from posterior uveitis and neuro-ophthalmologic conditions is crucial.
  • PPS is characterized by nasal macular fluid and occasional disc edema.