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Instantaneous Colorimetric and Fluorogenic Detection of Phosgene with a meso-Oxime-BODIPY
Tae-Il Kim1, Byunghee Hwang1, Jean Bouffard2
1Department of Chemistry and Research Institute of Basic Sciences, Kyung Hee University , 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.
Abstract:
The meso-oxime-substituted-1,3,5,7-tetramethyl BODIPY (1-oxime) was developed into a colorimetric and fluorogenic probe to selectively detect and quantify phosgene. The fast (<10 s) and sensitive (LOD = 0.09 ppb) phosgene detection is achieved by the conversion of the meso-oxime to the meso-nitrile, resulting in a large fluorescence turn-on response. The utility of 1-oxime was established for the visual detection of phosgene in solution and in a practical solid-state platform, making it a suitable candidate for on-site monitoring of phosgene gas exposure in the workplace.
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