Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

10.8K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
10.8K
Hand hygiene01:23

Hand hygiene

6.2K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
6.2K
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

1.1K
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
1.1K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

4.4K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.4K
Combined Effects of Drugs: Synergism01:27

Combined Effects of Drugs: Synergism

7.0K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
7.0K
Methods of Sterilization II: Chemical Methods01:30

Methods of Sterilization II: Chemical Methods

9.2K
In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
9.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrating Entrustable Professional Activities in Simulation-Based Health Care Education: A Systematic Literature Review.

Simulation in healthcare : journal of the Society for Simulation in Healthcare·2026
Same author

An education with audit and targeted feedback intervention to de-implement preoperative surgical urine cultures: a multi-center quasi-experimental study.

Infection control and hospital epidemiology·2026
Same author

16S rRNA Bacterial Identification in Evaluation of Orthopedic Infections and its Limited Role in Antimicrobial Stewardship.

Open forum infectious diseases·2026
Same author

Congenital rubella hospitalizations in Brazil: interpreting administrative data within the context of rubella elimination.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2026
Same author

Association between nocturnal asthma, symptom severity, and clinical outcomes: a systematic review.

The Journal of asthma : official journal of the Association for the Care of Asthma·2026
Same author

Association between pet ownership and incident dementia: A systematic review.

The American journal of medicine·2026
Same journal

Integrating patient in-hospital transfer patterns into automated outbreak detection systems: a single-center retrospective study.

Infection control and hospital epidemiology·2026
Same journal

Colonization with multidrug-resistant organisms (MDROs) including <i>Candidozyma auris</i> among residents in ventilator-designated versus non-ventilator-designated beds at skilled nursing facilities (SNFs).

Infection control and hospital epidemiology·2026
Same journal

Exploring unconventional antimicrobial stewardship models: options beyond traditional prospective audit and feedback.

Infection control and hospital epidemiology·2026
Same journal

Rectal versus groin screening for multidrug-resistant organisms: pathogen-specific diagnostic yield in a tertiary-care hospital.

Infection control and hospital epidemiology·2026
Same journal

Comparing rapid molecular and culture methods for detecting fungal contamination in healthcare environments.

Infection control and hospital epidemiology·2026
Same journal

Prospective validation and implementation of a model to identify patients with carbapenem-resistant Enterobacterales (CRE) carriage on admission to acute care hospitals.

Infection control and hospital epidemiology·2026
See all related articles

Related Experiment Video

Updated: Feb 18, 2026

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

27.8K

No-Touch Disinfection Methods to Decrease Multidrug-Resistant Organism Infections: A Systematic Review and

Alexandre R Marra1, Marin L Schweizer2, Michael B Edmond1

  • 11Office of Clinical Quality,Safety and Performance Improvement,University of Iowa Hospitals and Clinics,Iowa City,Iowa.

Infection Control and Hospital Epidemiology
|November 17, 2017
PubMed
Summary
This summary is machine-generated.

No-touch disinfection technologies like ultraviolet light (UVL) show promise in reducing healthcare-associated infections (HAIs). UVL effectively decreased C. difficile and VRE infections, but not MRSA or other multidrug-resistant organisms.

More Related Videos

A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens
09:02

A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens

Published on: June 7, 2017

19.8K
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.5K

Related Experiment Videos

Last Updated: Feb 18, 2026

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

27.8K
A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens
09:02

A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens

Published on: June 7, 2017

19.8K
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.5K

Area of Science:

  • Infectious Disease Epidemiology
  • Healthcare Management
  • Microbiology

Background:

  • Nosocomial pathogens contribute to healthcare-associated infections (HAIs).
  • No-touch disinfection technologies, including ultraviolet light (UVL) and hydrogen peroxide vapor (HPV), are emerging as strategies to combat pathogen transmission.
  • Previous studies suggest these technologies can limit the spread of dangerous pathogens within healthcare settings.

Purpose of the Study:

  • To systematically review and meta-analyze the impact of no-touch disinfection methods on reducing HAIs.
  • To assess the efficacy of UVL and HPV systems in decreasing infection rates for specific multidrug-resistant organisms (MDROs).

Main Methods:

  • A comprehensive literature search was conducted across multiple databases (PubMed, CINAHL, CDSR, DARE, EMBASE) up to April 2017.
  • Studies evaluating no-touch disinfection technologies and their effect on infection rates of Clostridium difficile, MRSA, VRE, and other MDROs were included.
  • Random-effect models were used to calculate pooled risk ratios (pRR) and assess heterogeneity.

Main Results:

  • Twenty studies (13 UVL, 7 HPV) were included in the meta-analysis.
  • UVL systems demonstrated a statistically significant reduction in C. difficile infection (CDI) (pRR, 0.64) and VRE infection rates (pRR, 0.42).
  • No significant reduction was observed for MRSA or gram-negative MDRO infection rates with UVL systems.

Conclusions:

  • Ultraviolet light (UVL) no-touch disinfection technology appears effective in preventing C. difficile and VRE infections.
  • Further research may be needed to evaluate the effectiveness of these technologies against other MDROs.
  • No-touch disinfection represents a potential advancement in infection control strategies for healthcare environments.