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    Global vaccination coverage for essential vaccines remains stagnant, with significant regional disparities. Improving immunization program performance is crucial to protect more children from preventable diseases.

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    Area of Science:

    • Public Health
    • Immunization Programs
    • Global Health Security

    Background:

    • The Global Vaccine Action Plan (GVAP) aims for 90% national vaccine coverage by 2020.
    • Monitoring global vaccination coverage is essential for disease prevention.

    Purpose of the Study:

    • To evaluate global and regional vaccination coverage trends up to 2016.
    • To assess changes in routine immunization schedule coverage.

    Main Methods:

    • Analysis of WHO and UNICEF global vaccination coverage estimates.
    • Evaluation of coverage for DTP3, polio, MCV1, and MCV2.
    • Assessment of vaccination dropout rates.

    Main Results:

    • Global DTP3, polio, and MCV1 coverage ranged from 84%-86% since 2010.
    • Vaccination dropout rates for the DTP series were 5% in 2016, highest in Africa (11%).
    • MCV2 coverage increased significantly between 2010 and 2016.

    Conclusions:

    • Sustained high vaccination coverage is necessary to protect populations from vaccine-preventable diseases.
    • Improvements in national immunization programs are critical to achieve GVAP goals.