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Economic Evaluations on Antimicrobial Stewardship Programme: A Systematic Review.

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Area of Science:

  • Health Economics
  • Infectious Disease Management
  • Hospital Administration

Background:

  • Antimicrobial resistance necessitates effective strategies.
  • Antimicrobial stewardship programmes (ASP) are crucial for optimizing antibiotic use.

Purpose of the Study:

  • To systematically review the cost-effectiveness of hospital-based antimicrobial stewardship programmes (ASP).

Main Methods:

  • Systematic literature search of EMBASE, PubMed/Medline, CINAHL, NHS, and CEA Registry (2000-2017).
  • Quality assessment using Joanna Briggs Institute and Consolidated Health Economic Evaluation Reporting Standards checklists.

Main Results:

  • Five studies were included, primarily cost-effectiveness analyses comparing ASP to standard care.
  • Studies considered provider (hospital) and payer (National Health System) perspectives.
  • Costs analyzed included personnel, ward, medical, and procedure costs.

Conclusions:

  • Included studies were generally well-conducted with good reporting quality.
  • Hospital ASP implementation appears to be cost-effective.
  • Limited comprehensive cost-effectiveness data exist, highlighting the need for more prospective studies with robust economic analyses.