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Avian Ganglioneuritis in Clinical Practice.

Giacomo Rossi1, Robert D Dahlhausen2, Livio Galosi1

  • 1Animal Pathology Section, School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93, 62024 Matelica, Italy.

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PubMed
Summary

Avian ganglioneuritis (AG) is a complex avian pathology linked to avian bornavirus (ABV). Research focuses on autoimmune causes and supportive management for affected birds.

Keywords:
Avian bornavirusAvian ganglioneuritisBornaviridaeProventricular dilatation disease

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Area of Science:

  • Avian medicine
  • Veterinary pathology
  • Virology

Background:

  • Avian ganglioneuritis (AG) is a complex pathology affecting birds worldwide.
  • Avian bornavirus (ABV) is a known cause of proventricular dilatation disease.
  • Avian Bornaviridae are genetically diverse and widespread in avian populations.

Purpose of the Study:

  • To investigate the intricate pathologies of avian ganglioneuritis (AG).
  • To explore the role of avian bornavirus (ABV) and other infective agents in AG.
  • To understand the autoimmune basis of AG, drawing parallels with human Guillain Barré syndrome.

Main Methods:

  • Research encompasses worldwide studies on avian pathologies.
  • Identification of avian bornavirus (ABV) as a causative agent.
  • Analysis of autoimmune mechanisms implicated in AG.

Main Results:

  • Avian bornavirus (ABV) is implicated in the autoimmune pathology leading to AG.
  • AG shares similarities with human autoimmune neuropathies like Guillain Barré syndrome.
  • Infective agents are key factors in the development of AG.

Conclusions:

  • Management strategies for AG focus on reducing neurological inflammation.
  • Supportive care includes managing secondary complications and nutritional support.
  • Further research into ABV and autoimmune links is crucial for avian health.