Impact of marital status on outcomes following ST-segment elevation myocardial infarction

Moo Hyun Kim1, Kwang Min Lee2, Soo Jin Kim3

  • 1Department of Cardiology, Dong-A University Medical Center, Busan, Republic of Korea; Clinical Trial Center, Dong-A University Medical Center, Busan, Republic of Korea.

Insights

Being married is associated with better cardiovascular outcomes and survival after ST-elevation myocardial infarction (STEMI) in Korean patients. This study highlights the importance of marital status for predicting major adverse cardiovascular events (MACE) in STEMI survivors.

Area of Science:

  • Cardiology
  • Social Science
  • Public Health

Background:

  • Mood disorders, depression, and loneliness are known risk factors for thrombotic occlusions.
  • Marital status may influence cardiovascular outcomes and survival post-ST-segment elevation myocardial infarction (STEMI), but evidence in Asian populations is limited.

Purpose of the Study:

  • To investigate the association between marital status and cardiovascular outcomes in Korean patients with STEMI.
  • To compare major adverse cardiovascular events (MACE) and mortality rates between married and widowed, divorced, or single (WDS) patients after STEMI.

Main Methods:

  • Retrospective analysis of 980 Korean patients with STEMI, categorized into married (n=780) and WDS (n=200) groups.
  • 1:1 matching for age and gender resulted in 172 patients per group.
  • Clinical characteristics and 1-year prognosis, including MACE and death, were collected and analyzed.

Main Results:

  • Widowed, divorced, or single (WDS) patients experienced significantly more MACE (44 vs. 26; p=0.016) and deaths (32 vs. 19; p=0.049) at 1 year compared to married patients.
  • WDS patients also had a shorter time to MACE occurrence (p=0.018).
  • No significant differences were observed in revascularization, stroke, major bleeding, or overall survival between the groups.

Conclusions:

  • Marital status appears linked to 1-year MACE and survival following STEMI in Korean patients.
  • Being married may be associated with improved vascular outcomes compared to being WDS.
  • Further large-scale studies, including national registries, are needed to validate these findings and extend the evidence beyond East Asian populations.
Abstract

Related Concept Videos

Close Relationships and Culture01:29

Close Relationships and Culture

Culture shapes how people approach attraction, choose partners, and build long-term relationships. While some preferences in mate selection appear consistent across cultures, such as men valuing physical attractiveness and women emphasizing financial resources, cultural contexts influence how these preferences are expressed and prioritized. Marriage extends beyond romantic ideals in many societies and is deeply embedded in social, economic, and religious frameworks.The Role of Culture in Mate...
258
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.1K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
477
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
309
Social Relationships and Well-Being01:30

Social Relationships and Well-Being

The significance of social relationships in psychological well-being is a well-established area of inquiry within social psychology. Research consistently demonstrates that the presence of meaningful, supportive relationships enhances emotional health, while the absence or deterioration of such connections can contribute to psychological distress. Relationships serve as a foundation for emotional support, identity, and social belonging, all of which are critical to an individual’s overall...
338
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
225