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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Postpartum depression in India: a systematic review and meta-analysis
Ravi Prakash Upadhyay1, Ranadip Chowdhury2, Aslyeh Salehi3
1Department of Community Medicine, Room 517, 5th floor, College Building, Department of Community Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.
Postpartum depression affects 22% of Indian mothers. Key risk factors include financial difficulties, domestic violence, and lack of spousal support, highlighting a critical need for enhanced maternal mental health services.
Area of Science:
- Reproductive Health
- Mental Health Epidemiology
- Sociology of Health
Background:
- Postpartum depression (PPD) poses a significant public health challenge globally.
- Limited data exists on the precise burden and contributing factors of PPD among Indian mothers.
- Understanding PPD prevalence is crucial for developing targeted interventions in maternal healthcare.
Purpose of the Study:
- To estimate the overall prevalence of postpartum depression (PPD) in Indian mothers.
- To identify significant risk factors associated with PPD in this population.
- To inform policy and resource allocation for maternal mental health in India.
Main Methods:
- A systematic literature search was conducted across PubMed, Google Scholar, and Embase databases (2000-2016).
- Meta-analysis using a random effects model was performed on 38 studies comprising 20,043 women.
- Quality assessment and publication bias were evaluated using the Newcastle-Ottawa scale and Egger's test, respectively.
Main Results:
- The pooled prevalence of postpartum depression (PPD) was estimated at 22% (95% CI: 19-25).
- Excluding early-onset PPD cases (within 2 weeks), the prevalence was 19% (95% CI: 17-22).
- Identified risk factors included financial difficulties, domestic violence, prior psychiatric history, marital conflict, lack of husband support, and having a female infant.
Conclusions:
- Postpartum depression (PPD) is highly prevalent among Indian mothers, indicating a substantial unmet need.
- There is an urgent requirement to increase resources for maternal mental health capacity-building in India.
- Addressing identified risk factors is essential for effective PPD prevention and management strategies.
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