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Rectal Carcinoma Case Causing Bicytopenia.

Sami Cifci¹, Aynur Ugur Bilgin², Murat Biyik¹

¹Department of Gastroenterology, Konya NEU Meram Faculty of Medicine, Turkey.

World Journal of Oncology

|November 18, 2017

Summary

Rectal carcinoma can cause severe bicytopenia due to bone marrow infiltration. This case highlights a rare presentation of solid tumors affecting blood cell production.

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Area of Science:

Hematology
Oncology
Pathology

Background:

Bicytopenia and pancytopenia are often caused by bone marrow infiltration.
Primary hematological malignancies like leukemia, lymphoma, and myeloma are common causes.
Solid tumor metastases to the bone marrow are a less frequent etiology.

Observation:

A patient presented with profound bicytopenia.
The condition was linked to diffuse bone marrow involvement.
The underlying cause was identified as rectal carcinoma.

Findings:

The rectal carcinoma led to extensive bone marrow infiltration.
This infiltration resulted in significant reduction of blood cell counts (bicytopenia).
The case demonstrates a rare association between rectal cancer and hematological abnormalities.

Keywords:

Bicytopenia Rectal carsinoma

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Implications:

Highlights the importance of considering metastatic solid tumors in unexplained bicytopenia.
Suggests a need for thorough oncological evaluation in patients with bone marrow infiltration.
Underscores the diverse clinical manifestations of advanced rectal carcinoma.