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Pediatric Otogenic Sigmoid Sinus Thrombosis: Case Report and Literature Reappraisal
Andrea Scherer1,2,3, Andrew Jea1,2,3
1Riley Hospital for Children, Indianapolis, IN, USA.
Abstract:
The purpose of this study was to review our experience with a single case of mastoiditis associated with sigmoid sinus thrombosis and increased intracranial pressure, and to review the experience of others through prior publications. We reviewed a case of a 6-year-old boy with an acute otitis media and mastoiditis, with associated ipsilateral sigmoid sinus and contralateral distal transverse sinus thrombosis. Based on the literature and our own experience, we conclude that most children with dural sinus thrombosis from acute otitis media and mastoiditis, in the setting of increased intracranial pressure, attain a good neurological outcome with a conservative neurosurgical approach. The mainstay of treatment seems to be appropriate antibiotic coverage and anticoagulation. Surgeries such as external ventricular drain, serial lumbar punctures, intracranial pressure monitor, and endovascular thrombectomy are reserved for patients with neurological deterioration despite maximal medical treatment.
Insights
Most children with mastoiditis, sigmoid sinus thrombosis, and increased intracranial pressure achieve good outcomes with conservative treatment. Antibiotics and anticoagulation are key, with surgery reserved for severe cases.
Area of Science:
- Pediatric Neurology
- Otolaryngology
- Infectious Diseases
Background:
- Mastoiditis, an infection of the mastoid bone, can lead to serious intracranial complications.
- Sigmoid sinus thrombosis (SST) is a rare but severe complication, often associated with acute otitis media.
- Increased intracranial pressure (ICP) can occur secondary to dural sinus thrombosis.
Purpose of the Study:
- To review a case of mastoiditis with sigmoid sinus thrombosis and increased intracranial pressure.
- To synthesize findings from existing literature on similar pediatric cases.
- To evaluate treatment outcomes and neurosurgical approaches.
Main Methods:
- Case report of a 6-year-old boy with acute otitis media, mastoiditis, and complex dural sinus thrombosis.
- Comprehensive literature review of pediatric mastoiditis complicated by sigmoid sinus thrombosis and increased ICP.
- Analysis of treatment strategies and neurological outcomes.
Main Results:
- The case involved a child with ipsilateral sigmoid sinus and contralateral distal transverse sinus thrombosis.
- Literature suggests a generally favorable neurological outcome in children treated conservatively.
- Conservative management, including antibiotics and anticoagulation, is often effective.
Conclusions:
- Most children with dural sinus thrombosis secondary to mastoiditis and increased ICP achieve good neurological outcomes with conservative neurosurgical management.
- Appropriate antibiotic therapy and anticoagulation form the cornerstone of treatment.
- Surgical interventions (e.g., external ventricular drain, endovascular thrombectomy) are reserved for refractory cases with neurological deterioration.
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