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Electrochemical Cobalt-Catalyzed C-H Oxygenation at Room Temperature
Nicolas Sauermann1, Tjark H Meyer1, Cong Tian1
1Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen , Tammannstraße 2, 37077 Göttingen, Germany.
Abstract:
Electrochemical cobalt-catalyzed C-H functionalizations were achieved in terms of C-H oxygenation under mild conditions at 23 °C. The robust electrochemical C-H functionalization was characterized by ample substrate scope, whereas mechanistic studies provided support for a facile C-H cleavage. The electrochemical cobalt-catalyzed C-H oxygenation proved viable on arenes and alkenes with excellent levels of positional and diastereo-selectivity, avoiding the use of stoichiometric silver(I) oxidants under ambient conditions.
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