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A New Murine Model of Endovascular Aortic Aneurysm Repair
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Renal Dysfunction Following Elective Endovascular Aortic Aneurysm Repair
Djodje Radak1, Mihailo Neskovic1, Petar Otasevic1
1Department of Vascular Surgery, Dedinje Cardiovascular Institute, Belgrade University School of Medicine, Belgrade 11040, Serbia.
Current Vascular Pharmacology
|November 19, 2017
Summary
Endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms may cause kidney injury. A multifactorial approach is needed to prevent acute kidney injury (AKI) and manage long-term renal outcomes after EVAR.
Area of Science:
- Cardiovascular Surgery
- Nephrology
- Vascular Medicine
Background:
- Abdominal aortic aneurysm (AAA) is a life-threatening condition.
- Endovascular aneurysm repair (EVAR) is a less invasive alternative to open repair (OR).
- Kidney damage is an emerging complication following EVAR.
Purpose of the Study:
- To review current evidence on renal impairment after EVAR.
- To discuss the incidence and quantification of acute kidney injury (AKI) post-EVAR.
- To explore strategies for preventing renal complications.
Main Methods:
- Review of recent human studies on EVAR and renal outcomes.
- Analysis of data on AKI incidence and long-term renal function.
- Evaluation of preventive strategies for kidney damage.
Main Results:
- The true incidence of AKI following EVAR remains uncertain.
- Long-term renal outcomes, especially with contrast exposure, require further investigation.
- A multifactorial approach is essential for AKI prevention.
Conclusions:
- Renal impairment is a significant concern after EVAR.
- Further research is needed to clarify AKI incidence and long-term effects.
- Proactive, multifactorial strategies are crucial for renal protection in EVAR patients.
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