Osteomyelitis After Calcium Phosphate Subchondroplasty A Case Report
Bulletin of the Hospital for Joint Disease (2013)
|November 20, 2017
Summary
Subchondroplasty, a minimally invasive procedure for bone marrow lesions, may lead to serious complications such as Staphylococcus aureus osteomyelitis. This case highlights the potential risks and need for further investigation into its safety and efficacy.
Area of Science:
- Orthopedic Surgery
- Biomaterials Science
- Infectious Disease
Background:
- Subchondroplasty involves injecting bone substitute into subchondral bone lesions for pain relief.
- It is marketed as a minimally invasive joint-preserving procedure with low complication risks.
- Prospective, randomized clinical trials on subchondroplasty efficacy are lacking.
Observation:
- A 64-year-old healthy male underwent subchondroplasty.
- The patient subsequently developed Staphylococcus aureus osteomyelitis.
- This infection necessitated surgical intervention and intravenous antibiotics.
Findings:
- Subchondroplasty can be complicated by serious infections like Staphylococcus aureus osteomyelitis.
- The efficacy and safety profile of subchondroplasty require further rigorous clinical evaluation.
- Bone substitute injections may carry risks beyond the intended therapeutic effects.
Implications:
- This case underscores the importance of considering infectious complications after subchondroplasty.
- Further research, including randomized controlled trials, is crucial to establish the true risk-benefit ratio of subchondroplasty.
- Clinicians should maintain a high index of suspicion for infection in patients presenting with new symptoms post-procedure.


