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Updated: Feb 18, 2026

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Age does not matter: Mobilization and harvesting are safe and effective for elderly allogeneic peripheral

Serkan Ocakci1, Selda Kahraman1, Seckin Cagirgan1

  • 1Department of Hematology, Medicalpark Izmir Hospital, Izmir, Turkey.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|November 21, 2017
PubMed

It took several years to succeed safe hematopoietic stem cell transplantations. HLA-matched unrelated donors have become the most common donor source for allogeneic hematopoietic stem cell transplants worldwide. The sibling donor may have more comorbidity and decreased regenerative potential of stem and immune cells. The purpose of this retrospective study was to examine whether aging had any negative effect on aging donor or patient. 27 patients who received a hematopoietic stem cell transplantation (HSCT) from February 2013 to May 2016 and their donors were analyzed. We showed that transplantation from older relative donor was feasible. Adverse event rate was low. Donors tolerated the procedure very well. Good CD34+ cell harvest was possible.

Keywords:
AgeAllogeneicDonor

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