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Right and left ventricular function in hospitalized children with respiratory syncytial virus infection

Thorsten Horter1, Britt Nakstad1,2, Omid Ashtari1

  • 1Department of Pediatric and Adolescent Medicine, Akershus University Hospital, Lørenskog.

Infection and Drug Resistance
|November 22, 2017
PubMed

Insights

Children with moderate respiratory syncytial virus (RSV) infection show increased cardiac output but maintained ventricular function. Routine cardiac ultrasound is not recommended for these patients.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Echocardiography

Background:

  • Respiratory syncytial virus (RSV) can cause extrapulmonary issues, including cardiac dysfunction in critically ill children.
  • Cardiac function in children with moderate RSV infection admitted to regular pediatric wards is not well understood.

Purpose of the Study:

  • To investigate cardiac function in hospitalized children with moderate RSV infection.
  • To assess left and right ventricular function and cardiac output using echocardiography.

Main Methods:

  • Echocardiography was performed on 26 pediatric patients (2 weeks to 24 months) with RSV infection.
  • Cardiac output and ventricular function were evaluated and compared with clinical parameters like s-troponin, oxygen use, and capillary refill time.

Main Results:

  • Left and right ventricular output were higher than published reference values.
  • Cardiac function remained well-maintained in most patients.
  • No significant correlation was found between cardiac parameters and oxygen support or capillary refill time.

Conclusions:

  • Children with moderate RSV infection exhibit increased ventricular output with preserved overall cardiac function.
  • Routine cardiac ultrasound is not indicated for moderate RSV cases.
  • The significance of elevated s-troponin in this population requires further investigation.
Abstract

Keywords:
bronchiolitiscapillary refill timechildechocardiographyrespiratory syncytial virus

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