Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aging01:26

Aging

874
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
874
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.8K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.8K
Mitochondria01:37

Mitochondria

20.8K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
20.8K
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

938
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
938
Longitudinal Research02:20

Longitudinal Research

13.5K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.5K
Erikson's Theory on Socioemotional Development during Adulthood01:27

Erikson's Theory on Socioemotional Development during Adulthood

995
Erik Erikson's theory of psychosocial development outlines a series of stages through which individuals progress across the lifespan. Each stage involves a psychosocial conflict that significantly influences personal growth and well-being. Three key stages — intimacy versus isolation, generativity versus stagnation, and integrity versus despair — highlight the developmental challenges faced in adulthood.
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
995

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PET-Based Personalized Management in Clinical Oncology: An Unavoidable Path for the Foreseeable Future.

PET clinics·2016
Same author

Evolving Role of Molecular Imaging with (18)F-Sodium Fluoride PET as a Biomarker for Calcium Metabolism.

Current osteoporosis reports·2016
Same author

Ocular Melanoma and Other Unusual Sites.

PET clinics·2016
Same author

Other PET Tracers and Prospects for the Future.

PET clinics·2016
Same author

Normal Variants and Effects of Aging on the Gastrointestinal Tract.

PET clinics·2016
Same author

PET and PET/CT in Pediatric Gastrointestinal Tract Oncology.

PET clinics·2016

Related Experiment Video

Updated: Feb 18, 2026

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

4.2K

Debate on human aging and lifespan.

Mohammad A Rafi1, Abass Alavi2

  • 1Department of Neurology, Jefferson Medical College, Philadelphia, Pennsylvanian, USA.

Bioimpacts : BI
|November 22, 2017
PubMed
Summary
This summary is machine-generated.

Human lifespan is debated, but scientific advances suggest aging will slow this century. This progress may extend human longevity significantly beyond the proposed 115-year limit.

Keywords:
Exosomal microRNAsFuturistsHuman agingLifespanMitochondrial damageNeuro-stem cellsNuclear DNA damageOptimistsRealists

More Related Videos

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine
08:53

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

1.7K
A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae
10:39

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae

Published on: September 17, 2020

6.8K

Related Experiment Videos

Last Updated: Feb 18, 2026

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

4.2K
Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine
08:53

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

1.7K
A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae
10:39

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae

Published on: September 17, 2020

6.8K

Area of Science:

  • Gerontology and biotechnology
  • Biomedical sciences and aging research

Background:

  • The scientific community has long debated the maximum human lifespan.
  • Recent research by Dong et al. proposed a limit of 115 years.

Discussion:

  • Advancements in biotechnology are rapidly improving our understanding of the aging process.
  • These improvements suggest that the rate of aging may decrease throughout the 21st century.

Key Insights:

  • Human longevity may exceed the 115-year limit previously suggested.
  • Continued progress in science and technology is key to extending lifespan.

Outlook:

  • The current century holds potential for significant increases in human longevity.
  • Further research in aging biology and regenerative medicine is anticipated.