Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

587
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
587
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

1.4K
Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
1.4K
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

394
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
394
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

585
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
585
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

460
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
460

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Persistent Severe Tricuspid Regurgitation After Mitral Transcatheter Edge-to-Edge Repair: Prognostic Implications of Guideline-Based Eligibility for Transcatheter Tricuspid Valve Intervention.

Structural heart : the journal of the Heart Team·2026
Same author

Temporal trends in mitral edge-to-edge repair for primary mitral regurgitation.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·2026
Same author

Prolonged Inflammation Associates With Greater Infarct Size and Poor Outcome After ST-Segment Elevation Myocardial Infarction.

JACC. Basic to translational science·2026
Same author

Coronary Artery Disease and Revascularization in T-TEER: Signal or Bystander?

JACC. Cardiovascular interventions·2026
Same author

Clinical Impact of Myocardium at Risk in Transcatheter Aortic Valve Implantation.

Circulation. Cardiovascular interventions·2026
Same author

Impact of lipoprotein(a) on the durability of aortic bioprosthetic valves.

Clinical research in cardiology : official journal of the German Cardiac Society·2026

Related Experiment Video

Updated: Feb 18, 2026

Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis
09:55

Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis

Published on: October 25, 2024

1.6K

Neoatherosclerosis: from basic principles to intravascular imaging.

Philipp Nicol1, Erion Xhepa2, Dmitry Bozhko3

  • 1German Heart Center Munich, Technical University of Munich, Munich, Germany - nicol@dhm.mhn.de.

Minerva Cardioangiologica
|November 22, 2017
PubMed
Summary

Neoatherosclerosis, new atherosclerotic lesions in stented vessels, presents challenges in diagnosis. This review covers histological findings and intravascular imaging (IVUS, OCT) for understanding this condition.

More Related Videos

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

4.6K
Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
08:01

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

7.8K

Related Experiment Videos

Last Updated: Feb 18, 2026

Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis
09:55

Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis

Published on: October 25, 2024

1.6K
Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

4.6K
Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
08:01

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

7.8K

Area of Science:

  • Cardiovascular Pathology
  • Medical Imaging

Background:

  • Neoatherosclerosis, characterized by new atherosclerotic lesions in the neointima of stented vessels, is a novel manifestation of atherosclerosis.
  • It often presents as in-stent restenosis (ISR) or in-stent thrombosis (ST), but its pathobiology remains incompletely understood.
  • Accurate diagnosis is hindered by limitations in current intravascular imaging resolution and a lack of histopathology correlation studies.

Purpose of the Study:

  • To provide a concise summary of the basic understanding and histological findings of neoatherosclerosis.
  • To focus on in-vivo findings using intravascular ultrasound (IVUS) and optical coherence tomography (OCT), discussing their advantages and limitations.
  • To explore recent advancements in molecular imaging techniques for improved examination of neoatherosclerotic plaques.

Main Methods:

  • Review of existing literature on neoatherosclerosis.
  • Analysis of in-vivo imaging data from intravascular ultrasound (IVUS) and optical coherence tomography (OCT).
  • Discussion of histological findings and molecular imaging advancements.

Main Results:

  • Intravascular imaging modalities like IVUS and OCT are the gold standard for diagnosing in-stent pathologies.
  • Understanding of neoatherosclerosis pathobiology is evolving, with imaging playing a crucial role.
  • Innovative molecular imaging techniques offer potential for more precise plaque examination.

Conclusions:

  • Neoatherosclerosis is a significant manifestation of atherosclerosis in stented vessels.
  • IVUS and OCT are essential tools for in-stent pathology diagnosis, despite limitations.
  • Future research directions include advanced molecular imaging for deeper insights into neoatherosclerosis.