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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Chronic Bowel Disorders: Introduction01:17

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Drugs for Treatment of Ulcerative Colitis in IBD01:29

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Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
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Diverticular colitis with progression to ulcerative colitis after sigmoidectomy.

Atsuyo Ikeda1, Tsunekazu Mizushima2,3, Yutaro Egashira4

  • 1Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan.

Clinical Journal of Gastroenterology
|November 23, 2017
PubMed
Summary

Diverticular colitis can transform into ulcerative colitis, particularly after colorectal surgery. This case highlights the potential for disease progression and suggests shared pathways between these inflammatory bowel conditions.

Keywords:
Colorectal surgeryDiverticular colitisPostoperative onsetUlcerative colitis

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Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Inflammatory Bowel Disease

Background:

  • Diverticular colitis involves chronic colon inflammation associated with diverticula.
  • Its findings can mimic ulcerative colitis, with some cases progressing to typical ulcerative colitis.

Observation:

  • A patient with sigmoid diverticulum underwent resection, followed by anastomotic leakage and colostomy.
  • Post-colostomy, the patient developed rectal bleeding and endoscopic signs of ulcerative colitis.

Findings:

  • Ulcerative colitis developed after colectomy for diverticular disease.
  • The patient showed a poor response to standard ulcerative colitis treatments, necessitating further surgery.

Implications:

  • Diverticular colitis may progress to ulcerative colitis, especially post-surgery.
  • This suggests potential pathogenic links and the influence of colorectal surgery on disease evolution.