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Computational prediction of the phenotypic effects of genetic variants: basic concepts and some application examples

Alejandro Sánchez-Gracia1, Sara Guirao-Rico2, Silvia Hinojosa-Alvarez1

  • 1a Departament de Genètica, Microbiologia i Estadística and Institut de Recerca de la Biodiversitat (IRBio), Facultat de Biologia , Universitat de Barcelona , Barcelona , Spain.

Journal of Neurogenetics
|November 24, 2017
PubMed

Keywords:
DNA sequence polymorphismFitness effectsamino acid variationcodon modelsdivergence ratesevolutionary conservationfunctional divergenceneutrality tests

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