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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

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 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
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Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

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Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
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Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

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Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
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Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

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Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
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Related Experiment Video

Updated: Feb 18, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
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[Symmetrical peripheral gangrene: 4 cases].

F Smaoui1, M Koubaa1, K Rekik1

  • 1Service des maladies infectieuses, université de Sfax, CHU Hédi Chaker, 3029 Sfax, Tunisie.

Annales De Dermatologie Et De Venereologie
|November 25, 2017
PubMed
Summary
This summary is machine-generated.

Symmetric peripheral gangrene (SPG) is a rare condition. Early diagnosis and treatment, especially in cases of Mediterranean spotted fever, are crucial for improving outcomes and potentially avoiding amputation.

Keywords:
Fièvre boutonneuse méditerranéenneGangrène périphérique symétriqueMediterranean spotted feverRickettsioseRickettsiosisSepticemiaSepticémieStreptococcus pneumoniaeSymmetrical peripheral gangrene

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Area of Science:

  • Vascular Medicine
  • Infectious Diseases
  • Dermatology

Background:

  • Symmetric peripheral gangrene (SPG) is a severe condition characterized by distal ischemic lesions on multiple extremities without proximal arterial obstruction or vasculitis.
  • SPG is a rare clinical entity requiring careful evaluation for underlying causes.

Purpose of the Study:

  • To describe the clinical presentation, etiological factors, and management strategies for symmetric peripheral gangrene (SPG).
  • To highlight the association between SPG and malignant Mediterranean spotted fever (MSF).

Main Methods:

  • Retrospective analysis of 4 SPG cases hospitalized between 2000 and 2014.
  • Inclusion criterion: distal ischemic damage at two or more sites without large vessel obstruction.

Main Results:

  • Four patients (mean age 43.2 years) presented with digital and toe tip necrosis.
  • Etiologies included Streptococcus pneumoniae bacteremia (2 cases) and malignant Mediterranean spotted fever (MSF) (2 cases).
  • Treatment involved antibiotics, iloprost, and heparin; 3 patients had favorable outcomes, while 1 required amputation.

Conclusions:

  • Symmetric peripheral gangrene can rarely complicate Mediterranean spotted fever.
  • Timely diagnosis and treatment through thorough skin examinations are vital for improving SPG prognosis.