Cardiac Biomarkers in Emergency Care
1Emergency Department, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Oxford Road, Manchester M13 9WL, UK; Cardiovascular Sciences Research Group, Core Technology Facility, Grafton Street, Manchester M13 9PL, UK; Healthcare Sciences Department, Manchester Metropolitan University, Oxford Road, Manchester M1 5GD, UK.
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This article critically reviews the latest evidence to guide the use of biomarkers for the diagnosis of acute coronary syndromes in practice. It shows how modern cardiac troponin assays can enable diagnoses to be ruled in or ruled out with a single blood test, with many more diagnoses confirmed or refuted in as little as 1 hour later. Finally, this article appraises the latest evidence for other cardiac biomarkers, such as heart-type fatty acid-binding protein and copeptin.
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