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Complication Rates After Total Hip and Knee Arthroplasty in Patients With Hepatitis C Compared With Matched Control

Jourdan M Cancienne1, Adrese M Kandahari, Aaron Casp

  • 1From the Department of Orthopaedics, University of Virginia Health System, Charlottesville, VA.

The Journal of the American Academy of Orthopaedic Surgeons
|November 28, 2017
PubMed

Insights

Patients with hepatitis C undergoing total hip (THA) or knee (TKA) arthroplasty face higher risks of infection, revision surgery, and medical complications. This increases healthcare costs and requires further investigation into hepatitis C

Area of Science:

  • Orthopedic Surgery
  • Hepatology
  • Public Health

Background:

  • Limited data exists on long-term outcomes for patients with hepatitis C undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA).
  • Hepatitis C infection may impact surgical outcomes and patient recovery.

Purpose of the Study:

  • To investigate the postoperative complication rates in patients with hepatitis C following THA and TKA.
  • To compare these complication rates with matched control groups.

Main Methods:

  • Database query for patients with hepatitis C who underwent THA and TKA.
  • Identification and comparison of postoperative complication rates (infection, revision, medical issues, transfusion) against matched control cohorts.

Main Results:

  • Patients with hepatitis C demonstrated higher rates of infection, aseptic revision surgery, medical complications, and blood transfusion post-THA and TKA.
  • These findings indicate an increased risk profile for this patient group.

Conclusions:

  • Patients with hepatitis C undergoing THA and TKA are at elevated risk for several postoperative complications.
  • This increased risk may lead to substantial rises in the cost of care.
  • Further research is necessary to quantify the association between hepatitis C and complications in total joint arthroplasty patients.
Abstract

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