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Fixation of Ultrasound Transducers for Spinal Cord Neuromodulation in Mice
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Magnetic transcutaneous fixation: an experimental study in pigs.

Michel L H T Vaena1, João P Sinnecker2, Thiago J S Vargas3

  • 1Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.

The Journal of Surgical Research
|November 29, 2017
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Summary

Magnetic subdermal implants can be safely fixed to the skin

Keywords:
ExperimentalImplantsMagnetic field therapySkinWound healing

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Area of Science:

  • Biomaterials Science
  • Dermatology
  • Biomedical Engineering

Background:

  • Magnetic subdermal implants for external device fixation are novel.
  • Excessive magnetic force can cause tissue necrosis due to compression.

Purpose of the Study:

  • Evaluate transcutaneous magnetic fixation feasibility.
  • Assess secondary skin changes from continuous static magnetic fields.

Main Methods:

  • Pig model with 72 subdermal implants.
  • Ultrasonography for implant depth measurement.
  • Computer simulations for safe magnetic attachment.
  • 7-day transcutaneous magnetic compression with varying magnet strengths.
  • Dermatopathological analysis of skin specimens.

Main Results:

  • 81% of magnetic fixation sites healed without complications.
  • Implant depths ranged from 4.6-8.3 mm with 13-37 mmHg pressure.
  • Stronger magnets increased dermal thickness and neovascularization.

Conclusions:

  • Transcutaneous magnetic fixation is viable in vivo under experimental conditions.
  • Continuous static magnetic field stimulation shows effects similar to pulsed electromagnetic fields.