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Ytterbium-Catalyzed Hydroboration of Aldehydes and Ketones
Weifan Wang1, Xingchao Shen1, Fengyi Zhao1
1College of Science, Nanjing Forestry University , Nanjing 210037, People's Republic of China.
Abstract:
The well-defined heavy rare-earth ytterbium iodide complex 1 (L2YbI) has been successfully employed as an efficient catalyst for the hydroboration of a wide range of aldehydes and ketones with pinacolborane (HBpin) at room temperature. The protocol requires low catalyst loadings (0.1-0.5 mol %) and proceeds rapidly (>99% conversion in <10 min). Additionally, catalyst 1 shows a good functional group tolerance even toward the hydroxyl and amino moieties and displays chemoselective hydroboration of aldehydes over ketones under mild conditions.
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