Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

2.0K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.0K
Allergic Reactions02:06

Allergic Reactions

32.5K
Overview
32.5K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

1.9K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
1.9K
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

21
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
21
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.5K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.5K
Antibody Structure01:10

Antibody Structure

65.8K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
65.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inhalant Mammal-Derived Lipocalin Allergens and the Innate Immunity.

Frontiers in allergy·2022
Same author

Single-cell characterization of dog allergen-specific T cells reveals T<sub>H</sub>2 heterogeneity in allergic individuals.

The Journal of allergy and clinical immunology·2021
Same author

Associations Between Neonatal Cry Acoustics and Visual Attention During the First Year.

Frontiers in psychology·2020
Same author

Commentary: Allergen and Epitope Targets of Mouse-Specific T Cell Responses in Allergy and Asthma.

Frontiers in immunology·2019
Same author

Improving competing voices segregation for hearing impaired listeners using a low-latency deep neural network algorithm.

The Journal of the Acoustical Society of America·2018
Same author

Reply to the letter to the editor concerning the review Immunotherapy for pet allergies.

Human vaccines & immunotherapeutics·2018

Related Experiment Video

Updated: Feb 18, 2026

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

24.0K

Immunotherapy for pet allergies.

Tuomas Virtanen1

  • 1a University of Eastern Finland, School of Medicine, Institute of Clinical Medicine , Department of Clinical Microbiology , Kuopio , Finland.

Human Vaccines & Immunotherapeutics
|November 29, 2017
PubMed
Summary

Pet allergen immunotherapy can effectively reduce symptoms for those with pet allergies. More high-quality studies are needed to confirm its long-term efficacy in managing allergic rhinoconjunctivitis and asthma.

Keywords:
allergen immunotherapyallergic asthmaallergic rhinitisallergycatsdogsmammalspetsrespiratory allergy

More Related Videos

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
04:35

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

Published on: December 27, 2024

1.0K
Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.9K

Related Experiment Videos

Last Updated: Feb 18, 2026

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

24.0K
Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
04:35

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

Published on: December 27, 2024

1.0K
Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.9K

Area of Science:

  • Allergy and Immunology
  • Environmental Health

Background:

  • Allergic diseases pose a significant health and economic burden.
  • Indoor allergens, particularly from pets like cats and dogs, contribute to allergic sensitization and respiratory conditions such as asthma.
  • Pet allergens are widespread, even in public spaces, complicating avoidance strategies.

Purpose of the Study:

  • To evaluate the effectiveness of allergen immunotherapy (AIT) as a treatment option for pet allergies.
  • To review current evidence on AIT for managing symptoms of allergic rhinoconjunctivitis and asthma caused by pet allergens.

Main Methods:

  • Review of existing literature on allergen immunotherapy for pet allergies.
  • Analysis of data from randomized controlled trials (RCTs) investigating AIT efficacy.
  • Assessment of symptom reduction and treatment outcomes in patients with pet allergies.

Main Results:

  • Allergen immunotherapy shows promise in reducing allergic symptoms associated with pet allergies.
  • Current evidence suggests AIT can be an effective treatment when conventional methods fail.
  • A limited number of high-quality RCTs exist, necessitating further research.

Conclusions:

  • Allergen immunotherapy is a potential therapeutic option for individuals suffering from pet allergies.
  • Further high-quality randomized controlled trials are required to solidify the evidence base for AIT in pet allergy management.
  • Optimizing AIT protocols may improve outcomes for allergic rhinoconjunctivitis and asthma patients.