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Updated: Feb 18, 2026
Author Spotlight: Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy
Published on: May 12, 2023
Optimization and Characterization of Paper-Made Surface Enhanced Raman Scattering (SERS) Substrates with Au and Ag
Silvia Dalla Marta1, Chiara Novara2, Fabrizio Giorgis3
1Department of Engineering and Architecture, University of Trieste, I-34127 Trieste, Italy. silviadallamarta@hotmail.it.
Abstract:
In this work, we present a systematic study on solid Surface Enhanced Raman Scattering (SERS) substrates consisting of Au and Ag nanoparticles (NPs) loaded on filter paper with the dip-coating method. The aim of this work is to explore how a series of parameters (e.g., concentration of colloidal solution, different porosity of filter paper, and the presence of an aggregating agent) affects the analytical performance of paper-based SERS substrates. All the substrates developed in this study have been analyzed with two non-resonant probe molecules, 4-mercaptobenzoic acid (4-MBA) and adenine, in terms of (i) inter-sample repeatability, (ii) intra-sample repeatability, (iii) sensitivity, and (iv) overall SERS performance in terms of analyte quantification. Moreover, the issue of how to evaluate the repeatability for a solid SERS substrate is carefully discussed.
