[The microcirculation of the myocardium based on scintigraphic data using labelled microspheres]

The authors described an original procedure for the determination of the organ blood flow with the help of 99mTc-labeled microspheres of aggregated albumin. Some features of the myocardial microcirculation in patients with CHD and without it were determined as well as interrelationships between the major coronary blood flow and the state of the myocardial microcirculation in various groups of CHD patients. A group of 32 males was examined. After thorough clinico-instrumental investigation CHD was diagnosed in 18 of them, 14 persons were taken as controls. Intraventricular administration of labeled microspheres during coronary angiography was followed by multipositional scintigraphy of the myocardium with further computer processing of images. A high sensitivity and specificity of the method was shown. The data obtained were compared with the results of other methods, among them those used by foreign researchers.