Noninvasive Intraocular Pressure Measurement in Animals Models of Glaucoma

Intraocular pressure (IOP) elevation is a critical risk factor for development and progression of glaucoma. As such, measuring IOP in animal models of the disease is important for any research work trying to understand the pathophysiologic mechanisms of glaucoma. Noninvasive IOP measurement in animals uses methods that have been adapted from use on humans. Calibration of the instruments used for the specific animal and even strain used is critically important for allowing meaningful comparisons of results. We describe below the methods used for noninvasive IOP measurement in animals that are relevant to glaucoma research.