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Oral cancer databases: A comprehensive review.

Gargi S Sarode1, Sachin C Sarode1, Nikunj Maniyar1

  • 1Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
|December 2, 2017
PubMed
Summary

This review highlights publicly accessible cancer databases, focusing on oral squamous cell carcinoma (OSCC). It details protein-coding gene and microRNA databases, aiding researchers in understanding oral cancer's molecular mechanisms.

Keywords:
databasemiRNAoral canceroral cancer-specific database

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Area of Science:

  • Genomics
  • Molecular Biology
  • Oncology

Background:

  • Oral cancer is a major global health concern.
  • Genomic technologies generate vast amounts of data on cancer-related genes and microRNAs.
  • Existing data necessitates collaboration and sharing for effective utilization.

Purpose of the Study:

  • To review publicly accessible databases relevant to oral squamous cell carcinoma (OSCC).
  • To provide comprehensive information on protein-coding gene and microRNA databases for OSCC research.
  • To facilitate the use of these resources for understanding oral cancer's molecular basis.

Main Methods:

  • Systematic review of publicly available cancer databases.
  • Identification and categorization of databases containing OSCC-specific information.
  • Analysis of gene overlap across different databases.

Main Results:

  • Identification of key protein-coding gene and microRNA databases pertinent to OSCC.
  • Description of gene overlap analysis to reduce research redundancy.
  • Highlighting the importance of data sharing and collaboration.

Conclusions:

  • Publicly accessible databases are crucial resources for oral cancer research.
  • Utilizing these databases can advance the understanding of oral cancer's molecular mechanisms.
  • This review aims to promote awareness and facilitate the use of these valuable resources.