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Updated: Feb 17, 2026

Procedure for Fabricating Biofunctional Nanofibers
Published on: September 10, 2012
Fe-polyaniline composite nanofiber catalyst for chemoselective hydrolysis of oxime
Sanjit Kumar Mahato1, Madhumita Bhaumik2, Arun Maji3
1Department of Civil and Chemical Engineering, University of South Africa (UNISA), PO Box 392, Pretoria 0003, South Africa.
Abstract:
A facile chemoselective one-pot strategy for the deprotection of oxime has been developed using Fe0-polyaniline composite nanofiber (Fe0-PANI), as a catalyst. Nano material based Fe0-PANI catalyst has been synthesized via in-situ polymerization of ANI monomer and followed by reductive deposition of Fe0 onto PANI matrix. The catalyst was characterized by FE-SEM, HR-TEM, BET, XRD, ATR-FTIR, XPS and VSM techniques. The scope of the transformation was studied for aryl, alkyl and heteroarylketoxime with excellent chemoselectivity (>99%). Mechanistic investigations suggested the involvement of a cationic intermediate with Fe3+ active catalytic species. Substituent effect showed a linear free energy relationship. The activation energy (Ea) was calculated to be 17.46 kJ mol-1 for acetophenone oxime to acetophenone conversion. The recyclability of the catalyst demonstrated up to 10 cycles without any significant loss of efficiency. Based on the preliminary experiments a plausible mechanism has been proposed involving a carbocationic intermediate.
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