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Updated: Feb 17, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
Primary Pulmonary Vein Leiomyosarcoma With Left Atrial Extension
Khaled Abdelhady1, Samarth Durgam1, Lona Ernst1
1Division of Cardiothoracic Surgery, Department of Surgery, The University of Illinois at Chicago, Chicago, Illinois.
This report details an extremely rare case of pulmonary vein leiomyosarcoma (LMS), a smooth muscle tumor, extending into the left atrium. Surgical resection was successfully performed for this aggressive tumor.
Area of Science:
- Cardiovascular Surgery
- Surgical Oncology
- Pathology
Background:
- Leiomyosarcoma (LMS) is a rare mesenchymal tumor arising from smooth muscle.
- LMS commonly affects the great vessels, particularly the inferior vena cava.
- Pulmonary vein LMS is an exceptionally rare presentation.
Observation:
- A case of pulmonary vein LMS invading the left atrium is presented.
- This tumor is aggressive and requires surgical intervention.
- The tumor was successfully resected.
Findings:
- The successful resection of a pulmonary vein LMS extending into the left atrium.
- Demonstrates the feasibility of surgical management for this rare tumor.
- Highlights the importance of considering rare tumor locations in differential diagnoses.
Implications:
- This case expands the understanding of LMS presentation and surgical possibilities.
- Contributes to the limited literature on pulmonary vein LMS.
- Informs surgical strategies for rare cardiovascular tumors.
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