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Updated: Feb 17, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Negative pressure therapy alone or with irrigation in the management of severe peritonitis
Background:
Ogilvie was the first to publish on open abdomen (OA) for the treatment of the damages caused by penetrating abdominal wounds in war events. Research improved those devices that allow a controlled, homogeneous and continuous extraction of contaminated fluids from all abdominal recesses, which are nowadays the base of the "Open Abdomen" technique.
Materials And Methods:
From August 2012 to February 2016 at the Department of Emergency Surgery of Cardarelli Hospital in Naples, 40 patients affected by Severe Peritonitis have been treated with OA technique. 13 (32,5%) were treated with only the suction-drainage system, 27 patients (67,5%) were treated with suction drainage and irrigation system. Abthera® device was used in all patients.
Results:
The duration of treatment was 15 days in the first group, with 7 device's substitutions, while in the second group it was about 10 days with 4 substitutions At the end of the procedure we were able to perform primary fascia closure in 7 cases (53,8%) in the first group and in 23 cases (85.2%) in the second group. 4 patients (30,8%) died in the first group, and 7 (26%) in the second.
Conclusion:
The suction/irrigation method seems to be appropriate to use in case of a surgical emergency that causes severe peritonitis. It is associated not only with lower death rates but also with better parameters, that are more frequently worse during prolonged treatments. Irrigation of abdominal cavity causes also less retraction of fascia recti which leads to a higher rate of direct fascia closure. Key Words: Emergency surgery, Irrigation, Open abdomen, Peritonitis.
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