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Related Concept Videos

Skin Cancer01:30

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Related Experiment Video

Updated: Feb 17, 2026

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
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Carcinoma en cuirasse.

Angela Alani1, Gerallt Roberts2, Olga Kerr1

  • 1Dermatology Department, Belfast Health and Social Care Trust, Belfast, UK.

BMJ Case Reports
|December 4, 2017
PubMed
Summary
This summary is machine-generated.

This case highlights advanced lobular breast carcinoma presenting as skin metastasis (carcinoma en cuirasse). This rare sign indicates advanced cancer with potential spread to liver and bone.

Keywords:
breast cancerdermatologygeriatric medicine

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Area of Science:

  • Oncology
  • Dermatology
  • Pathology

Background:

  • Lobular breast carcinoma is a common type of invasive breast cancer.
  • Cutaneous metastasis refers to the spread of cancer to the skin.

Observation:

  • A patient presented with carcinoma en cuirasse, a rare manifestation of advanced lobular breast carcinoma.
  • Further investigation revealed metastasis to the liver and bone.

Findings:

  • Carcinoma en cuirasse can be an initial presentation of advanced breast cancer.
  • This phenomenon is typically associated with breast cancer but can rarely occur with other adenocarcinomas, including lung, kidney, and gastrointestinal cancers.

Implications:

  • Highlights the importance of considering cutaneous metastasis in the differential diagnosis of skin lesions.
  • Emphasizes the need for thorough staging in patients presenting with skin metastases.
  • Underscores the diverse clinical presentations of advanced breast cancer and other adenocarcinomas.