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Updated: Feb 17, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Management of late presentation congenital heart disease
Parvathi U Iyer1, Guillermo E Moreno2, Luiz Fernando Caneo3
11Paediatric Intensive Care Unit,Fortis Escorts Heart Institute,New Delhi,India.
Insights
Timely diagnosis and repair of congenital heart diseases (CHDs) are often unfeasible in low- and middle-income countries. Late presentation of CHDs creates complex challenges for surgical candidacy and perioperative care.
Area of Science:
- Cardiology
- Pediatric Surgery
- Global Health
Background:
- Timely diagnosis and repair of congenital heart diseases (CHDs) are often not feasible in low- and middle-income countries.
- Economic development allows for cardiac units managing CHDs presenting later than ideal, missing early stabilization windows.
- Late presentation can lead to organ dysfunction, pulmonary vascular disease, and sequelae of cyanosis and polycythaemia.
Purpose of the Study:
- To highlight the challenges associated with late presentation of congenital heart diseases in resource-limited settings.
- To discuss the clinical and ethical considerations in managing patients with late-presenting CHDs.
- To inform strategies for surgical candidacy, operative planning, and intensive care for these complex cases.
Main Methods:
- Review of clinical scenarios and outcomes for patients with late-presenting CHDs.
- Analysis of challenges in decision-making regarding surgical intervention.
- Examination of perioperative intensive care management in resource-constrained environments.
Main Results:
- Late presentation of CHDs is common in low- and middle-income countries.
- Patients often present with significant organ dysfunction and complications.
- Decision-making regarding operability and surgical strategy is complex and ethically challenging.
Conclusions:
- Late presentation of CHDs poses significant clinical and ethical challenges.
- Effective management requires careful consideration of patient condition, surgical risks, and resource availability.
- Improved strategies are needed for the timely diagnosis and management of CHDs globally.
Abstract:
In many parts of the world, mostly low- and middle-income countries, timely diagnosis and repair of congenital heart diseases (CHDs) is not feasible for a variety of reasons. In these regions, economic growth has enabled the development of cardiac units that manage patients with CHD presenting later than would be ideal, often after the window for early stabilisation - transposition of the great arteries, coarctation of the aorta - or for lower-risk surgery in infancy - left-to-right shunts or cyanotic conditions. As a result, patients may have suffered organ dysfunction, manifest signs of pulmonary vascular disease, or the sequelae of profound cyanosis and polycythaemia. Late presentation poses unique clinical and ethical challenges in decision making regarding operability or surgical candidacy, surgical strategy, and perioperative intensive care management.
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