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[Studies on low volume priming heart lung bypass (author's transl)]
[Hokkaido Igaku Zasshi] the Hokkaido Journal of Medical Science
|March 1, 1975
Summary
Low volume priming extracorporeal circulation is feasible for open heart surgery. Surface cooling and hemodilution with 5% D/W offer reliable patient management during bypass.
Area of Science:
- Cardiovascular Surgery
- Cardiopulmonary Bypass
- Medical Device Technology
Context:
- Extracorporeal circulation (ECC) traditionally requires significant priming volume.
- Minimizing priming volume is crucial for patient safety, especially in specific populations.
- Zuhdi's heat exchanger and bubble oxygenator were utilized in this study.
Purpose:
- To evaluate the feasibility of low volume priming during extracorporeal circulation.
- To assess the efficacy of moderate hypothermia via surface cooling and hemodilution perfusion.
- To determine optimal priming solution volume and its impact on cardiac loading and blood viscosity.
Summary:
- Surface cooling before bypass provided more uniform temperature reduction than core cooling alone.
- A priming volume of approximately 20 ml/kg of 5% Dextrose in Water (D/W) was found feasible.
- Hemodilution with 5% D/W effectively reduced blood viscosity, with temporary postoperative effects.
- Excess lactate served as a reliable index for evaluating metabolic acidosis during ECC.
- Surface cooling aided in maintaining better acid-base balance during perfusion compared to core cooling alone.
Impact:
- Low priming volume perfusion combined with surface cooling hypothermia is a reliable technique for open heart operations.
- This technique may be applicable for extended perfusion durations.
- Findings contribute to optimizing cardiopulmonary bypass strategies for improved patient outcomes.