Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Immunological Memory01:23

Immunological Memory

17.1K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
17.1K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

10.1K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
10.1K
Active versus Passive Immunity01:31

Active versus Passive Immunity

11.1K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
11.1K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

9.2K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
9.2K
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

3.5K
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
3.5K
Development of Immunocompetence01:22

Development of Immunocompetence

1.0K
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epidemiological and clinical assessment of canine diabetes mellitus in Cocody, Abidjan, Republic of Ivory Coast.

Open veterinary journal·2026
Same author

Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress <i>in vivo</i>.

iScience·2025
Same author

Effector-Triggered Trained Immunity: An Innate Immune Memory to Microbial Virulence Factors?

Toxins·2022
Same author

Genomic evolution and adaptation of arthropod-associated Rickettsia.

Scientific reports·2022
Same author

Culturomics revealed the bacterial constituents of the microbiota of a 10-year-old laboratory culture of planarian species S. mediterranea.

Scientific reports·2021
Same author

Publisher Correction: Chryseobacterium schmidteae sp. nov. a novel bacterial species isolated from planarian Schmidtea mediterranea.

Scientific reports·2021

Related Experiment Video

Updated: Feb 17, 2026

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
09:24

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection

Published on: April 6, 2022

2.8K

[Trained immunity in invertebrates: what do we know?]

Cédric Torre1, Landry Laure Tsoumtsa1, Éric Ghigo1

  • 1URMITE (Unité de recherche sur les maladies infectieuses et tropicales émergentes), CNRS UMR 7278, IRD198, Inserm U1095, APHM, Institut hospitalier universitaire Méditerranée-Infection, Aix-Marseille Université, 19-21, boulevard Jean Moulin, 13385 Marseille Cedex 05, France.

Medecine Sciences : M/S
|December 5, 2017
PubMed
Summary

Trained immunity, or innate immune memory, enhances host protection against pathogens without acquired immunity. This review focuses on trained immunity mechanisms in invertebrates, offering a unique research model.

More Related Videos

Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection
11:16

Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection

Published on: April 21, 2015

11.3K
Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response
08:24

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Published on: January 12, 2017

8.4K

Related Experiment Videos

Last Updated: Feb 17, 2026

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
09:24

Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection

Published on: April 6, 2022

2.8K
Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection
11:16

Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection

Published on: April 21, 2015

11.3K
Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response
08:24

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Published on: January 12, 2017

8.4K

Area of Science:

  • Immunology
  • Invertebrate Biology

Background:

  • Trained immunity, a form of innate immune memory, enhances host defense against subsequent pathogen exposure.
  • Unlike acquired immunity, trained immunity relies on the innate immune system's cellular and molecular components.
  • While studied in vertebrates, trained immunity is also present in invertebrates.

Purpose of the Study:

  • To review the current knowledge of trained immunity in invertebrates.
  • To highlight the advantages of studying invertebrate models for understanding innate immune memory.
  • To emphasize the relevance of invertebrate models in trained immunity research.

Main Methods:

  • Literature review of studies on trained immunity in invertebrates.
  • Analysis of existing research on innate immune memory mechanisms.
  • Comparative assessment of invertebrate and vertebrate models.

Main Results:

  • Invertebrates possess functional trained immunity, demonstrating enhanced protection upon re-exposure to pathogens.
  • Mechanisms of invertebrate trained immunity involve innate immune cells and molecular pathways.
  • Invertebrate models offer a simplified system to study innate immune memory due to the absence of acquired immunity.

Conclusions:

  • Trained immunity is a conserved defense mechanism across different species, including invertebrates.
  • Further research in invertebrates can significantly advance our understanding of innate immune memory.
  • Invertebrate models are crucial for elucidating the fundamental principles of trained immunity.