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Cerebral Vasculitis in a Case of Meningitis
Devdeep Mukherjee1, Agnisekhar Saha2
1Department of Pediatric Medicine, Institute of Child Health Kolkata, India.
Insights
Pneumococcal meningitis can cause early cerebral vasculitis. High-dose steroids and antibiotics effectively treated a child with this condition, preventing neurological deficits.
Area of Science:
- Neurology
- Pediatrics
- Infectious Diseases
Background:
- Cerebral vasculitis is a severe complication of pneumococcal meningitis.
- It typically develops in the second week of illness, but early onset can occur.
Abstract:
Cerebral vasculitis is a serious complication of meningitis with Streptococcus pneumoniae. We report a 5 yr old girl who was admitted in May 2015 at Fortis Hospital, Kolkata, India and was diagnosed to have pneumococcal meningitis with vasculitis on DWMRI within a week of onset of fever. She was given high dose of methyl-prednisolone simultaneously with antibiotics and successfully treated without any neuro-sequelae. Although vasculitis has been documented to develop as sequelae to bacterial meningitis usually in the second week, our patient had an early presentation. Treatment with high dose steroid along with antibiotics resulted in dramatic improvement with no neurodeficit. DW-MRI is an important investigation to pick up early, evidence of vasculitis in a patient with meningitis who is showing neurological deteriorations despite improvement in blood parameters.
