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Is There any Association Between Celiac Disease and Helicobacter pylori?
Ahmet Uyanikoglu1, Huseyin Dursun2, Necati Yenice1
1Department of Gastroenterology, Harran University, Sanliurfa, Turkey.
Insights
This study found no significant correlation between celiac disease (CD) and Helicobacter pylori (H. pylori) infection, as prevalence rates were similar in both groups. Further research is recommended to explore potential links.
Area of Science:
- Gastroenterology
- Immunology
- Microbiology
Background:
- Celiac disease (CD) is an autoimmune disorder triggered by gluten ingestion.
- Helicobacter pylori (H. pylori) is a common bacterial pathogen affecting the upper gastrointestinal tract.
- The potential association between CD and H. pylori remains an area of investigation.
Purpose of the Study:
- To investigate the correlation between celiac disease and Helicobacter pylori infection.
- To compare the prevalence of H. pylori in patients diagnosed with CD versus a control group.
Main Methods:
- Retrospective analysis of patients diagnosed with CD and tested for H. pylori.
- Inclusion of a control group of patients undergoing gastroscopy and tested for H. pylori.
- Comparison of H. pylori prevalence between the CD and control groups.
Main Results:
- H. pylori prevalence was 48% in the CD group (15/31 patients).
- H. pylori prevalence was 53.4% in the control group (316/592 patients).
- The difference in H. pylori prevalence between the groups was not statistically significant (p > 0.5).
Conclusions:
- No statistically significant correlation was found between celiac disease and H. pylori infection.
- While H. pylori prevalence was slightly lower in celiac patients, the difference was not significant.
- Further studies are warranted to fully elucidate any potential relationship between CD and H. pylori.
Objective:
It was aimed to determine if there was a correlation between celiac disease (CD) and Helicobacter pylori (H. pylori) by comparing the prevalence of H. pylori in patients with and without CD.
Materials And Methods:
The patients who were diagnosed with CD and tested for H. pylori and the patients who presented for gastroscopy and tested for H. pylori were evaluated retrospectively and the prevalence of H. pylori was compared.
Results:
Fifteen (48%) of 31 patients who were diagnosed with CD and tested for H. pylori were males and had a mean age of 33.1 ± 12.7 years (17-72). In the CD group, H. pylori was positive in 15 patients (48%), and 592 antrum biopsy that was performed were included as the control group. Of these patients, 299 (50.5%) were males and had a mean age of 44.4 ± 17.05 years (16-96). Helicobacter pylori were positive in 316 patients (53.4%). Helicobacter pylori prevalence was similar in the groups with and without CD (p > 0.5).
Conclusion:
Although the prevalence of H. pylori was lower in celiac patients compared to the control group, the difference was not statistically significant. Although no findings suggesting a correlation between CD and H. pylori was found, further studies should be conducted.
How To Cite This Article:
Uyanikoglu A, Dursun H, Yenice N. Is There any Association Between Celiac Disease and Helicobacter pylori? Euroasian J Hepato-Gastroenterol 2016;6(2):103-105.
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