Related Experiment Video
Updated: Feb 17, 2026
07:13
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
5.3K
Advancing the Science and Practice of Medication Adherence
Michael J Stirratt1, Jeffrey R Curtis2, Maria I Danila2
1Division of AIDS Research, National Institute of Mental Health, Bethesda, MD, USA. stirrattm@mail.nih.gov.
Journal of General Internal Medicine
|December 6, 2017
Summary
Improving medication adherence is crucial for patient health. Recent innovations offer new ways to monitor and support patients, helping clinicians enhance adherence and treatment results.
Area of Science:
- Pharmacology and Patient Health Outcomes
- Behavioral Science in Medicine
Background:
- Medication adherence is a persistent challenge impacting patient outcomes.
- Advances in understanding adherence behavior are emerging.
- Current methods for supporting adherence require enhancement.
Purpose of the Study:
- To review recent advancements in medication adherence conceptualization and measurement.
- To outline multilevel strategies for improving and sustaining medication adherence.
- To provide recommendations for clinicians to leverage these innovations.
Main Methods:
- Literature review of recent advances in medication adherence.
- Synthesis of conceptual, measurement, and support strategies.
- Development of clinician-focused recommendations.
Main Results:
- Medication adherence is recognized as multifaceted and dynamic.
- Novel monitoring methods in clinical settings are available.
- Multilevel strategies can effectively improve and sustain adherence.
Conclusions:
- Clinicians can utilize recent innovations to improve patient medication adherence.
- Enhanced adherence positively impacts associated treatment outcomes.
- A dynamic and multilevel approach is key to optimizing adherence.
Related Concept Videos
01:28Drug Therapy
315
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
315
01:22Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems
228
Body:Bioavailability is a critical pharmacological concept that measures the extent and rate at which an active drug ingredient or therapeutic moiety enters the systemic circulation, remaining unchanged. It's a pivotal factor in determining a drug's efficacy and safety.The Biopharmaceutics Classification System (BCS) plays an essential role in drug development by categorizing drugs into four classes based on their solubility and permeability. This classification aids in understanding drug...
228
01:15Drug Dosing: Geriatric Patients
286
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
286
01:05Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
227
Body:Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
227
01:29Therapeutic Drug Monitoring: Affecting Factors
257
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
257
01:27Bioavailability Enhancement: Drug Permeability Enhancement
218
Body:After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt...
218