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Updated: Feb 17, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Borazine-CF3- Adducts for Rapid, Room Temperature, and Broad Scope Trifluoromethylation

Jacob B Geri1, Michael M Wade Wolfe1, Nathaniel K Szymczak1

  • 1Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, MI, 48109, USA.

Angewandte Chemie (International Ed. in English)
|December 6, 2017
PubMed

Keywords:
boronfluorinenucleophilic substitutionreaction mechanismswaste prevention

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