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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Study of Left Ventricular Mass and Its Determinants on Echocardiography
Namrata Guleri1, Susheela Rana2, Randhir S Chauhan3
1Senior Resident, Department of Anatomy, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
Insights
Increased Left Ventricular Mass (LVM) is linked to higher cardiovascular risk. This study found increased waist-hip ratio and higher fasting blood sugar are independent predictors of elevated LVM in Northern India.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Increased Left Ventricular Mass (LVM) is a significant independent risk factor for cardiovascular morbidity and mortality.
- Understanding LVM determinants is crucial for cardiovascular disease prevention strategies.
Purpose of the Study:
- To determine the prevalence and identify key determinants of Left Ventricular Mass (LVM) in the Northern Indian population.
- To investigate the association between LVM and various demographic and lifestyle factors.
Main Methods:
- A prospective, cross-sectional observational study was conducted over one year in a tertiary care center in Himachal Pradesh, India.
- Data included focused history, physical examination, and investigations for patients presenting with symptoms of dyslipidemia or hypertension.
- Statistical analysis involved calculating mean LVM index, p-values for significance, and Pearson correlation coefficients.
Main Results:
- The study population had a mean age of 42.30±9.8 years, with 62.9% males.
- Mean LVM index was significantly higher in men (77.7 ± 11.4) compared to women (71.3 ± 15.7) (p<0.01).
- A significant positive correlation was found between increased waist-hip ratio (WHR) and Left Ventricular Mass Index (LVMI) (r=0.3677, p=0.04).
Conclusions:
- Increased Left Ventricular Mass Index (LVMI) shows a positive and independent correlation with increased Waist Hip Ratio (WHR).
- Higher fasting blood sugar levels were also identified as having a positive independent correlation with increased LVMI.
- These findings highlight WHR and fasting blood sugar as important clinical indicators for assessing cardiovascular risk in this population.
Introduction:
Increased Left Ventricular Mass (LVM) is an independent risk factor for cardiovascular morbidity and mortality.
Aim:
This study was done to find the prevalence and determinants of LVM in the Northern Indian population.
Materials And Methods:
A prospective cross-sectional observational study was carried out in a tertiary care centre in Himachal Pradesh, India and the study population included all consecutive patients fulfilling the inclusion criteria attending cardiology OPD on seeking medical attention with various symptoms for dyslipidaemia, hypertension but not on medication over a period of one year. Focused history was taken; physical examination and investigations were done. Data collected was analysed using Epi-info software version 3.5.1. We calculated means of LVM index for categorical variables i.e., sex, tobacco consumption, alcohol consumption and sedentary lifestyle etc., and also calculated p-values as test of significance for mean difference across the exposure variable groups. The Pearson correlation coefficient was calculated and 2 tailed significance at p< 0.05 was taken as statistically significant.
Results:
Mean age of study population was 42.30±9.8 years and 62.9% were males. The mean LVM index was significantly higher in men than in women 77.7 ± 11.4 vs.71.3 ± 15.7 (p-value <0.01). Strong positive correlation was observed between increased waist hip ratio and increased Left Ventricular Mass Index (LVMI). The Pearson correlation coefficient was 36.77 and it was statistically significant with p-value 0.04.
Conclusion:
We found positive and independent correlation of increased LVMI with increased Waist Hip Ratio (WHR). A positive independent correlation was also observed with higher fasting blood sugar levels.
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