Study of Left Ventricular Mass and Its Determinants on Echocardiography

Namrata Guleri1, Susheela Rana2, Randhir S Chauhan3

  • 1Senior Resident, Department of Anatomy, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Insights

Increased Left Ventricular Mass (LVM) is linked to higher cardiovascular risk. This study found increased waist-hip ratio and higher fasting blood sugar are independent predictors of elevated LVM in Northern India.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Increased Left Ventricular Mass (LVM) is a significant independent risk factor for cardiovascular morbidity and mortality.
  • Understanding LVM determinants is crucial for cardiovascular disease prevention strategies.

Purpose of the Study:

  • To determine the prevalence and identify key determinants of Left Ventricular Mass (LVM) in the Northern Indian population.
  • To investigate the association between LVM and various demographic and lifestyle factors.

Main Methods:

  • A prospective, cross-sectional observational study was conducted over one year in a tertiary care center in Himachal Pradesh, India.
  • Data included focused history, physical examination, and investigations for patients presenting with symptoms of dyslipidemia or hypertension.
  • Statistical analysis involved calculating mean LVM index, p-values for significance, and Pearson correlation coefficients.

Main Results:

  • The study population had a mean age of 42.30±9.8 years, with 62.9% males.
  • Mean LVM index was significantly higher in men (77.7 ± 11.4) compared to women (71.3 ± 15.7) (p<0.01).
  • A significant positive correlation was found between increased waist-hip ratio (WHR) and Left Ventricular Mass Index (LVMI) (r=0.3677, p=0.04).

Conclusions:

  • Increased Left Ventricular Mass Index (LVMI) shows a positive and independent correlation with increased Waist Hip Ratio (WHR).
  • Higher fasting blood sugar levels were also identified as having a positive independent correlation with increased LVMI.
  • These findings highlight WHR and fasting blood sugar as important clinical indicators for assessing cardiovascular risk in this population.
Abstract

Related Concept Videos

Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
299
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
539
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
788
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
684
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
500
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
645